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179 Ass-deficient prostate and pancreatic cancers have also been shown to be sensitive to ADI-PEG20, and ADI-PEG20 promotes cell death by inducing autophagy and apoptosis

Aging Cell (2017) 16:83746

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5 Conclusion and outlook Cancer cells show overexpressed GSH that may maintain redox homeostasis to protect cells from oxidative damage, as well as reduce the chemotherapeutic agent-induced toxification

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The physiological and pathological role of acyl-coa oxidation