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Since this 2012 publication, there has been very little new research into this question

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Understanding the Regulatory Landscape The legal status of these peptides in the United States is complex

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Assays for Immunogenicity Assessment and Tools for Immunogenicity Reduction Pre-clinical Setting Due to the growing importance of mAb immunogenicity, there has been a growing need for tools to assess immunogenicity and reduce the propensity of mAbs to induce ADAs