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This process begins with tumors invading blood vessels and subsequently migrating into intrahepatic and extrahepatic tissues

The rebound of renal Cys levels in young and mature mice after 24 hr may indicate that hepatic efflux has returned to baseline levels, while the reduction of Cys in old mice may reflect a lower rate of GSH synthesis and turnover, possibly as a result of fasting as previously observed in old animals [64]

The disruption of one or more of these pathways may precipitate the retention of fat within the liver and the subsequent development of NAFLD

Organization of a functional glycolytic metabolon on mitochondria for metabolic efficiency

ROS attack/damage all cellular constituents [6], but especially biological membranes

doi: 10.1080/15563650903174828