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157 However, it is worth noting that utilizing specific nose-to-brain delivery pathways for exclusive drug transport to the brain necessitates further extensive research in this area

According to existing studies, immune senescence is characterized mainly by major features, such as thymic degeneration, changes in T-cell populations, senescent secretory phenotypes, dysregulation of immune responses, and metabolic and epigenetic changes, which affect cardiovascular diseases, neurodegenerative diseases, COVID-19, autoimmune diseases, and cancer[(150154), Figure 4]

et al., How Diet and Physical Activity Modulate Gut Microbiota: Evidence, and Perspectives, Nutrients

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Unweighted UniFrac distance analysis, reflecting phylogenetic community structure, demonstrated the greatest phylogenetic dissimilarity in the VPA-ASD group relative to controls (Figure S4C)