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PMID 17698324

At 6 and 12 months of age comparing WT and BACHD mice, our findings did not show remarkable differences between pro and anti-inflammatory cytokines in central and periphery tissues analyzed (Supplementary data, figures S47 and figures S1013)

These modifications disturb the balance of gut microbiota, compromise the intestinal barrier, and enhance accessibility, facilitating the entry of microbial metabolites and gut bacteria into the bloodstream

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This research suggested that the Modified GRF 1-29 analog might influence the growth hormone IGF-1 pathway