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Irrespective of its mechanism of action, cuprizone is a widely utilised and validated toxin for modelling CNS demyelination that is not directly associated with peripheral autoimmunity 20

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The questionnaires are designed to be completed by caregivers, but can also be administered by a trained examiner which will be done in the current study

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doi: 10.1016/j.biopha.2020.110984
