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MEKK1 signals trigger the IkB kinase complex (IKK) (Schulze-Osthoff et al

We also found no involvement of FGF-2 in Lu99 cell proliferation in vitro, but further studies are needed to confirm whether FGF-2 inhibition by its neutralising antibodies and multi-tyrosine kinase inhibitors targeting FGF receptors suppresses tumour growth of NSCLC cells including A549 cells, in which serum-free culture could not be adapted and FGF-2 expression was extremely lower than in Lu99 cells, through in vivo assays to test the anti-angiogenic effect
These OPCs are located along vessels and they show similarities with pericyte lineage cells [51]

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Gli1, which exerts a neuroprotective effect, induces the production of ganglionic neurons in the medial and lateral forebrain
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