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monocytogenes cytosolic lifecycle including Listeriolysin O (LLO) that facilitates cytosolic access, the phospholipase Cs (PLCs) that contribute to secondary vacuole escape, ActA which mediates intracellular motility and cell-to-cell spread, and the hexose phosphate transporter UhpT which contributes to cytosolic metabolism [13,22]

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Much lower dosages may also be effective since GHK-Cu's actions on cells generally occur at a 1 nanomolar concentration [68]