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Description
Effects of transmitters and amyloid-beta peptide on calcium signals in rat cortical astrocytes: Fura-2AM measurements and stochastic model simulations
Sensitivity Analysis Two sensitivity analyses were performed

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Once produced, TMA is absorbed into the bloodstream and transported to the liver, where it undergoes further oxidation to form TMAO via the enzyme FMO-3 [23, 25]

The higher plasma TMAO level was found to be predictive of poor long-term survival in patients without CKD (eGFR 60 ml/min) irrespective of cystatin C levels implying that increase in TMAO levels may occur before the renal insufficiency (i.e., rise in cystatin C) (Tang et al., 2015b)
