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In evaluating patients with primary breast cancer, including ChaC1 mRNA expression levels in the scoring model led to changes in chemotherapy decisions in 16% of patients (152)

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The increased activity of -secretases and concurrent reduction in the activity of -secretase may partially explain why melatonin treatment results in diminished A levels in the brains of both sporadic and transgenic animal models of AD [55,56,57]

Long-term clinical outcomes after early initiation of RRT in critically ill patients with AKI