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Fifty microliters of clodronate or control liposome was injected intratracheally every three days starting two days before the injection of bleomycin, until the end of the experiment

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M1/M2 macrophages in infection In vivo studies of macrophage polarization during infection have been confounded by the often-opposing signals pathogens and the host release to modulate macrophage behaviour towards an advantageous phenotype