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The MDH2 catalyzes the reversible oxidation of malate to oxaloacetate using NAD+/NADH as a cofactor in the citric acid cycle (45)

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Therefore, it is important to search for the mechanisms or diagnosis/screening of PD

Carvalho Pereira A, Violante IR, Mouga S, Oliveira G, Castelo-Branco M

further expanded the classification into four subtypes: proneural, neural, classical, and mesenchymal

The GSH/GSSG ratio in RBCs is used to measure the redox state of an organism, with reduced GSH typically constituting 9095% of the total GSH