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Diagnostic Frameworks and Emerging Biomarkers The accurate diagnosis of chronic pain, a prerequisite for effective management, hinges on distinguishing its underlying pathophysiological mechanisms, that is, nociceptive, neuropathic, and nociplastic

Aldehyde dehydrogenase 2 (ALDH2), a mitochondrial enzyme, metabolizes major lipid peroxidation products

Microcirculatory lesions A range of changes affecting the microcirculation in the nervous system may not produce ischemia or hemorrhage

Not because the molecule is wrong

Mrowicka M, Mrowicki J, Kucharska E, Majsterek I

Metabolic flexibility and nutrient addiction are critical for cell fate determination