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Figures 2b and c illustrate this relationship and demonstrate that the autism cases are clustered in the lower left quadrant of the graphs with decreased GSH/GSSG and aconitase activity relative to controls

Significance Statement Canonically, dopamine is recognized as a neurotransmitter involved in the regulation of movement, cognition, and reward

Macchi et al

Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair

By maintaining mitochondrial function and reducing ROS generation, SS-31 interrupts the cascade of events that leads to muscle protein degradation
