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[...] Edema will begin to appear in the morning as the person assumes erect posture, and progressively increases during the day, wrote the papers authors

Further supporting global heterogeneity, a 2024 metaanalysis published in Nature reported PD prevalence estimates ranging from 49 per 100,000 in SubSaharan Africa to 1081 per 100,000 in Latin America [39], figures that suggest even greater regional variability than captured in GBD estimates

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