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The function of the guiding bar, as postulated in our previous report 16 , could be strengthened by the crystal structure, and disruption of the guiding bar led to an increase in Trx-reduction efficiency, which further supports its importance for regulatory processes in catalysis of TrxR1

[Google Scholar] Cuming R

doi: 10.3389/fphar.2012.00059 9

Nat Immunol 12(8):715723 Bertl E, Bartsch H, Gerhauser C (2006) Inhibition of angiogenesis and endothelial cell functions are novel sulforaphane-mediated mechanisms in chemoprevention