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VGPR, very good partial response

Krivic A, Majerovic M, Jelic I, et al

Based on the encouraging clinical response seen with daratumumab-Kd in EQUULEUS [74], a phase III study (CANDOR) was conducted to further evaluate daratumumab-Kd in RRMM patients who had received 13 prior therapy lines [75]

Potential benefits include: To understand the 2026 update, it helps to start with what happened in 2023

Interestingly, the addition of 10 ng/mL IL-6 appeared to counteract some of the cytotoxic effects of high levels of TNF-, as cultures treated with both 10 ng/mL IL-6 and 100 ng/mL TNF- no longer show a significant increase in extracellular LDH as compared to controls (Figure 5C)

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