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Aggravated accumulation of S disrupts mitochondrial biogenesis and function by dysregulating the AMPK-CREB-PGC-1 pathway (Shi et al., 2005), which regulates Sirt3 and mitochondrial defence (Park et al., 2020), reported that restoration of Sirt3 expression through the AMPK agonist 5-aminoimidazole-4-carboxamide riboside (AICAR) could recover mitochondrial dynamics and mitophagy

144 These inhibitors hold promise for slowing disease progression and preserving cognitive function in affected individuals

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Characterization of the fe (III)-tiron system in solution through an integrated approach combining NMR relaxometric, thermodynamic, kinetic, and computational data

BCL-2, the proto-oncogene, has the ability to block apoptosis, leading to reduced cell death and an enhanced proliferation (Omar et al., 2019)