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Dimethyl sulfoxide (DMSO) A solvent that may be used for its permeability properties But long-term use may have potential toxicity

A serum B12 level is the starting point

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A 2020 preclinical toxicity review found no serious toxicity in mice, rats, rabbits, or dogs at tested doses, but longterm human carcinogenicity or organtoxicity data are missing

Loren Pickart, who noticed that factors in younger human plasma could push older tissue toward a more youthful repair response
