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(2010) for both strongly and weakly internalizing opioids (except etorphine, which has extremely high affinity for MOR) is consistent with this interpretation
doi: 10.1177/0748233710387007

Bobescu E, Marceanu LG, Dima L, Balan A, Strempel CG, Covaciu A

Cell 106 , 5970 (2001)

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