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The relative abundance of potentially harmful genera, such as Fusobacterium, Porphyromonas , and Prevotella , is markedly elevated in patients with PCOS, whereas Lactobacillus and Bifidobacterium , which are involved in butyrate production and barrier maintenance, exhibit synchronous depletion ( Lobetyolin, a polyacetylene glycoside extracted from the roots of Codonopsis pilosula , is a crucial quality indicator of this herb (Wang J

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Acta 1830 (6), 38463857

Data indicate it may modulate the expression of over 4,000 human genes [4]

doi: 10.1016/0006-2952(84)90416-7
