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The inhibition profile of methylene blue on nitrovasodilator induced cyclic guanosine monophosphate accumulation was quantitatively reproduced by extracellular generation of superoxide anion with xanthine (100 uM) and xanthine oxidase (5 mU)

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Conclusion: Evidence Does Not Support the pH Incompatibility Claim The scientific evidence provides no support for claims that reconstituting the copper tripeptide, thymosin fragment, and body protection compound together causes degradation due to pH incompatibility