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The adoptive transfer of IL15-activated NK cells can induce a delay in the growth of the MB DAOY cell line in a subcutaneous xenograft mouse model (160), leading to an increase in the OS rate

3 Although alteration of antioxidant enzymes has been implicated in glaucomatous ONH astrocytes, 6 it remains unknown whether oxidative stress alters the mitochondrial network and triggers bioenergetic dysfunction in the ONH astrocytes

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Additionally, we summarize the relationship and commonality among glutamate excitotoxicity, oxidative toxicity, and immunoexcitotoxicity in order to posit a holistic view and molecular mechanism of glutamate toxicity in PD