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Additionally, ERG, with a standard redox potential (E 0 = 0.06 V), exhibits lower reactivity, greater resistance to autooxidation, and higher chemical and thermal stability compared to most thiols in organisms, such as glutathione (E 0 = 0.24 V), lipoic acid, vitamin C, and vitamin E (E 0 = 0.2 to 0.32 V) [16,22]

[DOI] [Google Scholar] 112.Britto D.T., Kronzucker H.J

Glutathione is subsequently found at its highest concentrations in tissues at most risk and therefore requiring the most protection from potentially toxic exogenous and endogenous compounds: the liver where the vast majority of detoxification metabolism occurs and, at the cellular level, around organelles which are most exposed and most at risk of potential damage from oxidative stress from reactive oxygen species: mitochondria, peroxisomes and the nuclear matrix (Wu et al., 2004)

Combining Human Disease Genetics and Mouse Model Phenotypes towards Drug Repositioning for Parkinsons disease

Int J Mol Sci 25(13):7274 Dimitriadis K, Adamopoulou E, Pyrpyris N, Sakalidis A, Leontsinis I, Konstantinidis D (2023) Effect of SGLT2 inhibitors on the endothelium and the microcirculation: from bench to bedside and beyond

Scopoletin shows inhibitory activity in enzymatic assays of XO in vitro (506)
