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Molecular docking, which was based on the CHARMm force field, was applied for each phytochemical compound with the different targeted receptors 33,34 , using vina software packages

COUP-TFII acts downstream of Wnt/beta-catenin signal to silence PPARgamma gene expression and repress adipogenesis

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As far as how you use those two pieces together, that's the way to do it and that's the most research

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It is possible that there is a bidirectional link between the two rather than a causal one-way relationship