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for example, AGI-5198, an IDH1-mutant inhibitor, which was investigated for its properties to inhibit IDH1-mutant glioma by reducing 2-HG levels and inducing cell differentiation, or HMS-101, an IDH1-mutant inhibitor capable of inducing the apoptosis of primary IDH1-mutant AMLs and of reducing 2-HG levels

Partial hepatectomy in dogs

Acknowledgments We thank Universidad del Rosario for the administrative support with this publication

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The same controls were used for three of the studies [47, 49, 50]

4 Delivery Systems for Cancer Vaccines Significant limitations, including low efficacy, side effects, poor tumor penetration, and increased toxicity, often hinder the effectiveness of immunotherapy and lung cancer vaccines (Lahiri et al., 2023)