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NRF2 Nuclear factor erythroid 2-related factor 2 [56] is a fundamental local transcription element that promotes resistance to ferroptosis and is crucial for preserving the balance of antioxidants and metabolic stability in cells [56]

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Glutathione synthesis and its role in redox signaling

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Intracellularly, GSH has the prominent role of acting as the redox buffer to protect the proper folding of proteins