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Furthermore, bicyclol and glycyrrhizin prevent ferroptosis-induced liver and brain injury, respectively, by activating the GPX4 pathway in vivo [194,195]
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Autophagy 13 , 868884 (2017)
Moreover, CF airway inflammation is due to an excessive neutrophil recruitment, triggered by extrinsic and intrinsic factors, and by an imbalance between reduced concentrations of anti-inflammatory molecules (IL-10, lipoxins, chemotaxis inhibitors, and neutrophil activators) and higher levels of pro-inflammatory proteins (calprotectin)
