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An investigation on the antimutagenic properties of South African herbal teas

In addition, GSTO1 overexpression has been documented in breast cancer cell lines 16,17 and has a role in the development of drug resistance 7,18,19

Disulfide stress: a novel type of oxidative stress in acute pancreatitis

In cases where contamination occurred due to poor technique, injection site reactions may also appear

However, the active ingredients, preservatives, and excipients in these formulations may collectively damage cellular structures, ultimately causing alterations and instability of the tear film ( These factors contribute to the development of glaucoma-related ocular surface disease (G-OSD), a condition that often goes underdiagnosed but is estimated to affect 40%59% of glaucoma patients worldwide (Tovar et al., 2022)

The ATM-Chk2-cell division cycle 25A (Cdc25A)-cyclin-dependent kinase 2 (Cdk2) pathway acts as a genomic integrity checkpoint and guards against radioresistant DNA synthesis ( Activating transcription factor 3 (ATF3) belongs to ATF/cAMP-responsive element-binding protein (CREB) family ( MDM2 is an E3 ubiquitin ligase that carries out the final step in the ubiquitination cascade, catalyzing transfer of ubiquitin from an E2 enzyme to form a covalent bond with a substrate lysine ( Pregnane X receptor (PXR, NR1I2, SXR) belongs to the nuclear receptor superfamily and is mainly expressed in normal liver, small intestine, colon, duodenum, and gall bladder tissues ( In this study, we investigated the role and the mechanism of PXR in the protection of liver and colon cancer cells from IR-induced DDR