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Looking forward, mRNA therapies could be applied to other cardiac conditions as well: for instance, to induce controlled regeneration by expressing developmental factors (a controversial but intriguing idea where mRNA for factors like cyclins or fetal genes are delivered to try to coax adult cardiomyocytes to proliferate)

Velloso FJ, Bianco AF, Farias JO, Torres NE, Ferruzo PY, Anschau V, et al

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Pro-inflammatory and proatherogenic mCRP, but not nCRP, induces ROS monocyte/macrophage production and facilitates macrophage uptake of necrotic cells (192) contributing to foam cell formation, atherosclerotic plaque formation and plaque rupture or destabilization (190, 191)

Flavonoid diosmetin increases ATP levels in kidney cells and relieves ATP depleting effect of ochratoxin A

Biochim Biophys Acta Mol Basis Dis 1407: 215224