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With chemotherapy drugs gradually discovered to enhance anti-tumor immunity by inducing Immunogenic Cell Death (ICD), Gao and his team explored the potential of DSF/Cu as an ICD inducer and its ability to enhance the efficacy of immune checkpoint blockade in HCC

Supplemental injections of glutathione can help detoxify and protect the body from the additive effects of aging

Drug-resistant cancer cells adapt to TME features such as hypoxia, nutrient deprivation, and reduced cellcell contact, forming a unique microenvironmentcell phenotype synergistic network

Recent studies have shown that glutamine-derived -KG regulates the differentiation of CD4(+) T cells into Th1-type effector T cells or Treg cells via DNA methylation and lipid homeostasis 135,136

Can enhancing melatonin in middle-age, when the decline begins, slow the accumulation of oxidative damage and reduce the incidence of neurodegenerative disease decades later

Sheleg et al