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3.4 Cytotoxicity assay The cytotoxicity of SBA-15 MSN, FA-SNCD@SBA-15, FA-SNCD@SBA-15/ENZ and free ENZ in PC3 cell lines was evaluated using the MTT assay (to assess in vitro toxicity)

Results In 317 individuals aged 3 months to 86 years, mitochondrial function was analyzed separately in isolated PBMCs and isolated platelets

Dose-Response Patterns Documented by Sources Animal models tested doses ranging from micrograms to hundreds of micrograms per kg, with no toxicity ceiling reached

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academic.oup.com , doi:10.3945/ajcn.110.003483

Leucine-rich repeat kinase 2 (LRRK2) regulates -synuclein clearance in microglia