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Using nuclear magnetic resonance (NMR) spectroscopy, Smeland and colleagues also demonstrated increased levels of norepinephrine and serotonin in the cortex of healthy mice, after 25 days of treatment with acetylcarnitine at a daily dose of approximately 0.5 g/kg body weight [117]

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A major route of action is controlling fatty acid metabolism, as previously mentioned

[7] Although SPCD is an autosomal recessive condition, heterozygotes have been shown to be at an increased risk for developing benign cardiomyopathy compared to wild type individuals

Additionally, a single in vitro fertilization (IVF) attempt also failed

They concluded that perhaps LC does not interact with CrNic to cause improvement in reproductive parameters [20]