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WRKY33pro:EYFP-NLS (Col-0) and CBP60gpro:EYFP-NLS (Col-0) were generated as described in the subsection Promoter-reporter imaging 66

2012;5:ra77

Furthermore, gut dysbiosis reduces the activity of bile salt hydrolase and 7-dehydrogenase, leading to decreased levels of secondary bile acids (e.g., lithocholic acid) and insufficient activation of TGR5

doi: 10.1016/0076-6879(87)47121-8

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In some cases, especially for individuals with digestive issues or malabsorption conditions, the efficiency of oral supplementation can be severely compromised, leading to nutrient deficiencies despite adequate intake