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Astragaloside IV can also enhance pancreatic beta cell dysfunction induced by uric acid through the activation of the PI3K/AKT pathway, anti-apoptotic effects, and activation of autophagy (Zhang et al., 2021)

This is mechanistically distinct from proton pump inhibitor pharmacology and is part of why the peptide attracts interest as a research tool for ulcer biology and NSAID-induced gastric injury

Peptides: Building Blocks of the Human Body Peptides are short chains of amino acids, which are the building blocks of proteins in the human body

Nature (2010) 468(7323):52732

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