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Extrinsic factors can also affect the response to treatment, including pH, hypoxia, and paracrine signaling interactions between stromal and other tumor cells (47, 48)

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Furthermore, the pathophysiology of PD involves numerous signaling pathways, including inflammatory signaling pathways like NF-B and NLRP3 inflammasome

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The next day, media were removed, and 100 L of 1.25 M oligomycin solution or 100 L of 2-DG (22.5 mM solution) was added

4 Risk Factors Gallstone formation is influenced by interactions between genetic, metabolic, and environmental factors (Pak 2016)