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According to the occurrence time, RD is divided into acute RD (ARD), occurring approximately 23 weeks following the initial irradiation, and CRD, occurring at least 90 days or even years after radiotherapy

doi: 10.1517/14712598.2011.619974

More preclinical studies are needed to optimize iron metabolism regulation protocols in various iron overload conditions and to explore the best treatment strategies to reduce iron levels

These points of intersection make it possible to simultaneously target both death modalities, an approach that is expected to produce a synergistic killing effect [65,66,67]

DSIP Reported Research-Context Dose Ranges Pattern Older human trials Typical Range 25 nmol/kg Route IV Notes Short 4-7 night courses

10.7759/cureus.29696 [DOI] [PMC free article] [PubMed] [Google Scholar] Huot J., Houle F., Marceau F., Landry J