what is transdermal glutathione Topical vs Oral Glutathione: Which Better for Skin? How to Order Transdermal Glutathione
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International Journal of Molecular Sciences, 25 (7), 3797

Buddiga says you should

Xerosis is associated with atopic dermatitis, hand eczema and contact sensitization independent of filaggrin gene mutations

Overexpression of c-MYC renders metformin-treated cells refractory to the metabolic effect of the drug, suggesting the functional relevance of c-MYC modulation for the effects of metformin (Fig

Use Anti-Itch Creams: Over-the-counter hydrocortisone creams or antihistamine lotions can help soothe the itchiness and calm the skin

But you should talk to your doctor before mixing treatments
