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This tunnel, essential to bypassing the glycocalyx, changes shape depending on the protonation state of key residues in the SSD and pSSD, to transport the sterol to the luminal membrane for membrane integration (Fig 1A) (14, 22)
[DOI] [PubMed] [Google Scholar] 25.Nelson DR, Cooper JN, Lalezari JP, Lawitz E, Pockros PJ, Gitlin N

The goal in research contexts is harm reduction, not harm elimination

They form when years of sunlight push the pigment-making cells in one patch of skin into overdrive

Recognising the limits of non-surgical care can be the first step toward considering other options without judgment
