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Accordingly, the identified M-QTLs are best interpreted as integrative, trait-weighted genomic regions rather than uniform tolerance loci, and trait-resolved M-QTL analyses remain an important avenue for future refinement

10.1126/science.6338593 Science 156 TekinS

Its key advantages are prolonged sterility (multi-dose use) and slight anesthetic effect, but it must be used correctly: always dilute drugs per guidelines, ensure the final solution is isotonic, and heed contraindications (no neonates, no intrathecal use)

PMID: 41203627 Cell Rep Microglial macrophage-derived ds-HMGB1 in DRG orchestrates neuropathic pain through immune-neural signaling

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