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Conclusion: Sucrosomial vitamin B12 demonstrated superior efficacy in rapidly and consistently elevating and maintaining higher circulatory B12 levels compared to conventional supplements

The transcobalamin-vitamin B12 complex is also known as holotranscobalamin (HoloTC), which represents the biologically active form of cobalamin and allows for cellular uptake of vitamin B12 through specific cell surface transcobalamin receptors[3]

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Week 1: 1 mg (1000 mcg) once daily to assess tolerability

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The fecal microbiota of patients with primary biliary cholangitis (PBC) causes PBC-like liver lesions in mice and exacerbates liver damage in a mouse model of PBC