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The long-term intravenous (IV) application of OHCbl is impracticable for the patients

doi:10.1038/nm759

Composite fillings, for example, are widely used biocompatible materials

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The isoalloxazine ring of riboflavin absorbs energy from UVA radiation through photosensitisation, leading to the formation of singlet oxygen and other reactive oxygen species, which have the potential to cause damage to nearby molecules [64]

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