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Probiotic administration reduces intestinal leakage by, among others, affecting intestinal immunoregulation and anti-inflammatory effects (for example, an increase in sIgA production), anti-inflammatory effects, strengthening the epithelial barrier (for example, an increase in the synthesis of mucin and short-chain fatty acids (SCFAs), and the production of bacteriocins, which limit the growth of pathogenic microorganisms (for example, defensin) [8, 133, 134]

This decrease contributes to various age-related issues, including cognitive decline, decreased energy production, and increased oxidative stress, making supplementation potentially beneficial for older adults.

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J Neurosci 27 : 52605264

doi: 10.1016/0003-9861(88)90487-0

This is a rarity as it has been struck in BLACK