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Ongoing research is necessary to explore and harness the repigmentation abilities of the emerging therapies discussed above while minimizing potential side effects (Table 2)

(1964) postulated a hypothesis indicating a positive correlation between the levels of histone acetylation and methylation and the activation of gene transcription

Cell Mol Life Sci 76:41314144

10.1016/j.physbeh.2015.12.008 203 LabunskyyV

Moulson AJ, Squair JW, Franklin RJM et al (2021) Diversity of reactive astrogliosis in CNS pathology: heterogeneity or plasticity

Next, Cys58 nucleophilically attacks the sulfide of Cys58, releasing a GS- anion, which picks up a solvent proton and is released from the enzyme, forming the second GSH