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Weight-associated health problem: Several health problems stem from carrying excess body weight, including but not limited to type 2 diabetes, cardiovascular disease, hypertension, and sleep apnea

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Following ischemic stroke, activation of COX-2 and LOXs leads to excessive production of prostaglandins and leukotrienes, which amplify microglial activation, increase cytokine release, and promote further neuronal injury (Kloska et al., 2020

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