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it also significantly impacts emotional well being , and is associated if not the cause of depression, anxiety, loss of sleep, and non compliance with treatment 22

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While insufficient choline intake is linked to liver dysfunction, neurodegeneration, and muscle damage, excessive intake primarily results in mild cholinergic side effects such as sweating, diarrhea, hypotension, and fishy body odor, with a tolerable upper intake level of 3.5 g/day in adult individuals (5759)

Published 2018 May 24

Thrombolytic agents: Therapy modification should be considered due to chance of increased adverse effects of thrombolytics

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