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In contrast to skeletal muscle and liver, less than 5% of the glucose taken up by adipocytes is stored as glycogen

55:407-419 For several decades the guidelines for treatment of hypercholesterolemia have focused on LDL-C levels both for risk stratification and as the principal target of therapy to prevent ASCVD

However, research into its mechanism and metabolic effects continues to provide valuable insights into selective fat tissue targeting

Such content must not be interpreted as providing definitive diagnosis, prognosis, or treatment selection for any individual, and it is not a substitute for conventional diagnostic methods, where clinically appropriate, unless expressly supported by the patients individualized evaluation

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Proc Natl Acad Sci U S A 93(3):12651269 Lopez-Erauskin J, Galino J, Ruiz M, Cuezva JM, Fabregat I, Cacabelos D, Boada J, Martinez J, Ferrer I, Pamplona R, Villarroya F, Portero-Otin M, Fourcade S, Pujol A (2013) Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy