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Perhexiline, a CPT1 inhibitor, induces a metabolic shift from fatty acid to glucose oxidation, triggering a complex rebalancing of carbon and nucleotide phosphate fluxes

This dehydrogenase is expressed at high levels in liver, brain, pancreas and kidney, but not in muscle

It is extensively utilized in both the pharmaceutical and food industries

Electrophilic Fatty Acid Nitroalkenes Are Systemically Transported and Distributed upon Esterification to Complex Lipids

86 (Pt 2), 396419 (2022)

Conversely, 9( R )- and 13( R )-HODEs are not ligands for this receptor and resulted in increased cell growth and DNA synthesis through a different mechanism, most likely via activation of the COX pathway