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Increased prolidase activity and oxidative stress in PCOS

In a mouse model of streptozotocin-induced diabetes with hyperglycemia, high glucose not only increased neutrophil infiltration but also impaired the activity of peroxisome proliferator-activated receptor (PPAR), a transcription factor for lactoferrin (Ltf) encoded by the PPAR gene

Many peptides act as signaling molecules, growth factors, neurotransmitter-related compounds, or regulatory messengers

Because we're going to be able to go in and turn off or on a gene and fix that problem right at the cellular level, at the biological level, you're going to be able to fix and remediate so many of these issues
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Geiss K, et al
