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Both procedures take 1020 minutes per wrist
J Endocrinol 160 : 247255 Norrelund H et al

In the Preiss-Handler pathway: nicotinic acid (NA) is converted into NAMN via the catalytic activity of NA phosphoribosyltransferase

It burns through nicotinamide, which your cells would otherwise recycle into NAD+, and it spends SAM, the body's main methyl currency

doi: 10.1177/00045632221087132

By doing so, it helps regulate blood sugar levels in individuals with type 2 diabetes